Month: March 2020

The novel coronavirus COVID-19 uses the SARS-coronavirus receptor ACE2 and TMPRSS2 a cellular protease for entry into target cells

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The highly pathogenic coronavirus, COVID-19, emerges in China in 2019, and its rapid national and international spread creates a global health emergency. Coronaviruses use their spike proteins to select and enter target cells and insights into COVID-19 spike (S)-driven entry might facilitate the assessment of pandemic potential and reveal therapeutic targets. COVID-19 coronavirus and the … Read more

World health organization launches mega SOLIDARITY trial for testing four coronavirus treatments

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The World Health Organization (WHO) recently announced a global trial of four coronaviruses (COVID-19) treatments, and the name given to this trial is “SOLIDARITY trial,” according to science magazine. The attempt is designed to rapidly gather the data on the drugs to figure out any side effects and to find the most effective treatments for … Read more

Therapeutic options for the new novel coronavirus COVID-19.

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The 2019 novel coronavirus COVID-2019 has spread rapidly since its recent identification in patients with severe pneumonia in Wuhan, China. As of 31 march 2020, COVD-19 have more than >823,197 cases worldwide, with most confirmed cases in USA ~174,750, with an estimated mortality risk of ~5% and ~2% respectively. Unfortunately, no vaccine or drug has … Read more